Frasier Crane, the psychiatrist from Cheers, returns to Seattle to host a radio phone-in and ends up sharing his smart apartment with his father Martin, a retired policeman, Martin's dog and Daphne, his English live-in carer. Frasier's even fussier brother Niles, also a psychiatrist, and Roz, his producer, complete a circle of snobbery, farce and family rivalry.